PhD candidate 'Structural Glycoproteomics'

At Radboudumc, you will work in a highly collaborative, interdisciplinary, and international environment. We are a leading European center for genomic medicine and rare disease research, with strong connections to clinicians, patients, and the academic + industrial analytical chemistry field. What sets us apart is our unique position at the interface of fundamental research on glycoproteomics and translational research on genetic disease applications involving clinicians and patients. This ensures that your work will have clinical relevance and impact.

You will join a group that performs (pre-)clinical research on genetic glycosylation disorders aiming to improve diagnostics, understand disease mechanisms and develop treatments. Our team consists of senior scientists, technicians, PhD students, and post-docs with multidisciplinary expertise of glycoproteomics, glycobiology, analytical chemistry, and informatics.

The position is based at Radboudumc in Nijmegen, the Netherlands. Radboudumc is internationally renowned for its research and diagnostics on a variety of genetic disorders and the impact of personalized medicine. The position is primarily housed in the department of Human Genetics with a strong collaboration with Bruker Daltonics. Our department offers an exciting working environment with enthusiastic people from many parts of the world, providing ample critical mass and a stimulating, collaborative atmosphere for high quality research.

At the department of Human Genetics, you work on the diagnosis and treatment of hereditary disorders in patients and their families. You work in the outpatient clinic or in the laboratory for diagnostic testing, where genetic, metabolic, and neurochemical analyses are performed. In addition, you contribute to research exploring the relationship between genes and disease.

As a leading, multidisciplinary department, you provide high quality genetic healthcare and contribute to scientific progress.

You bring curiosity, creativity, and energy to the team. Proactive and self-driven, you take initiative and thrive in collaborative environments, working effectively with colleagues both within and beyond the department. You are motivated, communicative, hardworking, and adaptable, always keeping the team’s goals and success firmly in focus.

Your Profile:

• Candidates must have completed a MSc degree in Chemistry, Molecular Life Sciences, or a related field.
• Hands-on experience with mass spectrometry.
• Experience with chemometrics and informatics (Python programming).
• Solid theoretical background in molecular and cell biology and experience with glycoproteomics or glycomics will be considered a strong plus.
• Self-motivated, project-oriented work ethic with collaborative and team player attitude.
• Effective communication, writing and presentation skills in English for multidisciplinary audience.
• Plan and perform scientific experiments in an independent manner.
• Critically analyze data.
• Report results.
• Take a leading role in writing manuscripts.
• Present data at local, national and international scientific meetings.
• Supervise MSc and/or BSc students.
• Active participation in group discussions.

• Our software solution "Myriad" is at the basis of our glycoproteomics work which is, or will be, implemented in Bruker GlycoScape and Matrix Science MASCOT, respectively.
• For more information about BioBeyond_NL and its activities.
• Learn more about recent developments and applications in structural glycoproteomics.
• This position requires a Certificate of Conduct (VOG).

We are recruiting for this position ourselves. Unsolicited marketing is not appreciated, but do feel free to share the vacancy in your network!