PhD candidate 'Modulating the tumor microenvironment to enhance radiosensitivity'

At the Radiotherapy & OncoImmunology (ROI) lab of the department of Radiation oncology, ~ 20 researchers aim at better understanding how tumor cells interact with the surrounding tumor microenvironment (TME), and how these interactions influence response to cancer treatment, with a particular focus on radiotherapy.

Research is centred around the complex interplay between tumor cells, cancer-associated fibroblasts (CAFs), immune cells and other components of the TME. We aim to identify and therapeutically target TME features that contribute to treatment resistance, and to develop strategies that enhance the efficacy of radiotherapy. Our work combines imaging, molecular, cellular and immunological approaches, ranging from mechanistic studies to preclinical in vivo models.

The ROI lab is located within the department of Radiation Oncology, allowing for frequent interaction between basic and translational research and clinical practice. This provides an excellent environment for translating mechanistic insights into novel therapeutic strategies.

Requirements

• An MSc degree in Biomedical Sciences, Biology, Cancer Biology, or a related field, or an equivalent degree,
• A strong interest in preclinical cancer research,
• Motivated to investigate biological mechanisms underlying treatment response,
• Curious, enthusiastic about experimental science, and enjoy working in an interdisciplinary research environment.

Experience with molecular and cellular biology, tumor biology, radiobiology or immunology is an advantage. Experience with preclinical animal models is welcome, and candidates holding an Article 9 certificate for working with experimental animals are especially encouraged to apply.

• This position requires a Certificate of Conduct (VOG).

We are recruiting for this position ourselves. Unsolicited marketing is not appreciated, but do feel free to share the vacancy in your network!